3,3'-diindolylmethane

1. 3,3'-diindolylmethane decreases muscle atrophy in mouse cells.

   “DIM attenuated DEX-induced myotube atrophy while promoting myotube differentiation.”

   Cellsdexamethasone-induced myotube atrophy

   3,3'-Diindolylmethane ameliorates muscle atrophy by modulating mitochondrial function and calcium homeostasis

   Phytomedicine : international journal of phytotherapy and phytopharmacology·11 Jun 2026

More on Muscle atrophy

1. 3,3'-diindolylmethane extends lifespan in worms.

   “extending lifespan of C. elegans.”

   Model organismsnatural aging

   3,3'-Diindolylmethane ameliorates muscle atrophy by modulating mitochondrial function and calcium homeostasis

   Phytomedicine : international journal of phytotherapy and phytopharmacology·11 Jun 2026

1. 3,3'-diindolylmethane improves grip strength in mice.

   “DIM demonstrated therapeutic promise by enhancing grip strength and myofiber quality in mice”

   Animalsdexamethasone-induced muscle atrophy

   3,3'-Diindolylmethane ameliorates muscle atrophy by modulating mitochondrial function and calcium homeostasis

   Phytomedicine : international journal of phytotherapy and phytopharmacology·11 Jun 2026