WEE1
GeneHomo sapiens1 paper2 findingsHGNC 12761NCBI Gene 7465Taxon 9606
- Cells1
Interventions
1INTERLEUKIN-1 beta
downin human cells1
1 study
INTERLEUKIN-1 beta
downin human cells1
INTERLEUKIN-1 beta decreases WEE1 in human cells.
“In IL-1β-treated C28/I2 cells, WEE1 mRNA decreased whereas CDK6 mRNA increased; representative immunoblots showed concordant qualitative trends.”
CellsC28/I2
Senescence-Associated Checkpoint Gene Dysregulation in Established Osteoarthritis: Integrated Transcriptomic Analysis and In Vitro Evaluation of CDK6 and WEE1 · Biomedicines · 26 Aug 2026
Associations
1Osteoarthritis
downin silico1
1 study
Osteoarthritis
downin silico1
Osteoarthritis is associated with WEE1 in silico (AUC 0.792).
“CDKN1A, CDK6, and WEE1 were reduced in OA-associated meniscal samples in GSE98918; within-dataset ROC analyses yielded AUCs of 0.931, 0.882, and 0.792, respectively.”
In silicomeniscus
Senescence-Associated Checkpoint Gene Dysregulation in Established Osteoarthritis: Integrated Transcriptomic Analysis and In Vitro Evaluation of CDK6 and WEE1 · Biomedicines · 26 Aug 2026