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USP4

1 paper

Model organisms1

Latest

Nature Aging·4 Sep

The aging factor EPS8 induces disease-related protein aggregation through RAC signaling hyperactivation

Experiments in wormsMechanisms

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EPS81
FUS1
Huntington's disease1
Proteostasis1
TARDBP1
Ubiquitin–proteasome system1
Amyotrophic lateral sclerosis1
ced-101
eps-81
Neurodegenerative disease1
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Korea University secures ₩8.3 billion for AI-assisted gut microbiota-derived rejuvenation drug developmentFundinghealtho.co.kr and 3 more

Nicotinamide riboside shows no benefit in 410-person phase 3 trial for early Parkinson’sTrialsDeutsches Ärzteblatt

Human autophagy does not uniformly decline with age, researchers reportResearchScienceDaily and 1 more

Trials

Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and WomenResults posted 13 Oct 2026, Marquette University Fisetin for Improving Vascular Function in Older Adults: A Phase II Clinical TrialPhase 2Registered 13 Oct 2026, University of Colorado, Boulder ELITE: Deep Profiling and Algorithmic Polytherapy to Map Individual Response in Healthy AgingPhase 2Registered 13 Oct 2026, Sheba Medical Center

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MenopauseDisease16 papers this week, usually 1 Depressive symptomsDisease26 papers this week, usually 4 Nicotinamide ribosideInterventionNicotinamide riboside did not improve early Parkinson disease PregnancyExposureEstimated brain-age gap rises by three years in pregnancy LifestyleExposureGenetic risk and lifestyle linked to estimated brain aging Vitamin DInterventionSevere vitamin D deficiency is linked to higher death rates

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Mechanisms264 Interventions477 Biomarkers458 Populations631 AI & data179 Industry & policy24

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