UBE2C

Gene

4 papers3 findings

HGNCNCBI GeneTaxon

  • 3 independent labs in 1 country
  • Funder: Science and Technology Project of Nantong City
  • Humans1
  • Animals1
  • Cells2

Interventions

2

Platelet-rich plasma

upin human cells1

1 study
  1. Platelet-rich plasma increases UBE2C in human cells.

    “PRP treatment significantly upregulated UBE2C expression in OA-FLSs”

    Cellsin OA-FLSssynovial fibroblasts

    Mechanism of platelet-rich plasma inhibiting inflammatory response, oxidative stress, and senescence in synovial fibroblasts of patients with knee osteoarthritis via UBE2C based on transcriptome sequencing analysis

    Journal of bioenergetics and biomembranes26 Mar 2026

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Serial passaging

downin human cells1

1 study
  1. Serial passaging decreases UBE2C in human cells.

    “KIFC1 and UBE2C were down-regulated in late-phase UC-MSCs, which were involved in the maintenance of stemness.”

    Cellslate passage (P15) vs early passageumbilical cord mesenchymal stem cells

    Whole transcriptome scanning and validation of negatively related genes in UC-MSCs

    Heliyon12 Mar 2024

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Upstream

1

Sepsis-induced acute respiratory distress syndrome

upin mice1

1 study
  1. Sepsis-induced acute respiratory distress syndrome increases UBE2C in mice.

    “E2f2, Ezh2, and Ube2c genes had a higher expression in the sepsis-induced ALI/ARDS subgroup than in the control subgroup”

    Animalsin sepsis-induced ALI/ARDS mouse model

    Machine learning methods identified cellular senescence-related hub molecules in sepsis-induced acute respiratory distress syndrome (ARDS) and their upstream regulatory network

    Molecular biology reports6 Jun 2026

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