TUSC2
Gene1 paper3 findings
- Animals1
Effects
3Protein aggregate size
downin mice1
1 study
Protein aggregate size
downin mice1
TUSC2 decreases protein aggregate size in mice.
Animalsshown by knockouthippocampusmales
Mitochondrial calcium sensor Tusc2 protects the aging hippocampus from proteostasis collapse in a sex-specific manner · Mechanisms of ageing and development · 19 Sep 2026
Integrated stress response
downin mice1
1 study
Integrated stress response
downin mice1
TUSC2 inhibits integrated stress response in mice.
Animalsshown by knockouthippocampusmales
Mitochondrial calcium sensor Tusc2 protects the aging hippocampus from proteostasis collapse in a sex-specific manner · Mechanisms of ageing and development · 19 Sep 2026
Oxidative phosphorylation
upin mice1
1 study
Oxidative phosphorylation
upin mice1
TUSC2 activates oxidative phosphorylation in mice.
Animalsshown by knockouthippocampusmales
Mitochondrial calcium sensor Tusc2 protects the aging hippocampus from proteostasis collapse in a sex-specific manner · Mechanisms of ageing and development · 19 Sep 2026
Funding
National Institute on AgingUS$218.3k1 grant since 2026