AgingResearch.NewsJoin free

TNFRSF25

Gene

1 paper2 findings

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals1

Interventions

1

Brain-derived exosomes from aged mice

upin mouse cells1

1 study

  1. Brain-derived exosomes from aged mice increases TNFRSF25 in mouse cells.

    “A-Exo could upregulate the expression of tumor necrosis factor receptor superfamily member 25 (Tnfrsf25) in neurons”

    Cellsin neurons

    Brain-derived exosomes from aged mice accelerate cognitive decline in repeated mild traumatic brain injury by activating neuronal Tnfrsf25

    Experimental gerontology16 Oct 2025

More on Brain-derived exosomes from aged mice

Effects

1

Apoptosis

mediatesin mouse cells1

1 study

  1. TNFRSF25 mediates apoptosis in mouse cells.

    “Knockdown of Tnfrsf25 reversed A-Exo-induced apoptosis, confirming its mechanistic role.”

    Cellsin A-Exo treated cells

    Brain-derived exosomes from aged mice accelerate cognitive decline in repeated mild traumatic brain injury by activating neuronal Tnfrsf25

    Experimental gerontology16 Oct 2025

More on Apoptosis

Latest

Related