AgingResearch.NewsJoin free

spartin

There is 1 paper on spartin in aging research: none in people yet, 1 in cells.

Gene

1 paper studies it4 findings

NCBI GeneTaxon

See all 1

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: FWF Austrian Science Fund
  • 4 of 4 findings with company ties
  • Cells1

Effects

4

necrosis

downin yeast cells1

1 study

  1. spartin decreases necrosis in yeast cells (Heterologous expression of human or Drosophila spartin).

    “heterologous expression of human or Drosophila spartin extends chronological lifespan of yeast, reducing age-associated ROS production, apoptosis, and necrosis.”

    CellsHeterologous expression of human or Drosophila spartin

    Mitochondrial energy metabolism is required for lifespan extension by the spastic paraplegia-associated protein spartin

    Microbial cell (Graz, Austria)

Apoptosis

downin yeast cells1

1 study

  1. spartin decreases apoptosis in yeast cells (Heterologous expression of human or Drosophila spartin).

    “heterologous expression of human or Drosophila spartin extends chronological lifespan of yeast, reducing age-associated ROS production, apoptosis, and necrosis.”

    CellsHeterologous expression of human or Drosophila spartin

    Mitochondrial energy metabolism is required for lifespan extension by the spastic paraplegia-associated protein spartin

    Microbial cell (Graz, Austria)

More on Apoptosis

Age-associated ROS production

downin yeast cells1

1 study

  1. spartin decreases age-associated ROS production in yeast cells (Heterologous expression of human or Drosophila spartin).

    “heterologous expression of human or Drosophila spartin extends chronological lifespan of yeast, reducing age-associated ROS production, apoptosis, and necrosis.”

    CellsHeterologous expression of human or Drosophila spartin

    Mitochondrial energy metabolism is required for lifespan extension by the spastic paraplegia-associated protein spartin

    Microbial cell (Graz, Austria)

More on Age-associated ROS production

Chronological lifespan

upin yeast cells1

1 study

  1. spartin extends chronological lifespan in yeast cells (Heterologous expression of human or Drosophila spartin).

    “heterologous expression of human or Drosophila spartin extends chronological lifespan of yeast”

    CellsHeterologous expression of human or Drosophila spartin

    Mitochondrial energy metabolism is required for lifespan extension by the spastic paraplegia-associated protein spartin

    Microbial cell (Graz, Austria)

Latest

Related