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SEMA3C

There are 2 papers on SEMA3C in aging research: none in people yet, 1 in animals. The newest story, Nov 9, 2026: “A heart support cell group sustains nerves and pumping in mice”.

Gene

2 papers study it1 finding

HGNCNCBI GeneTaxon

1 new paper in 30 daysSee all 2 papers on SEMA3C

At a glance

The findings reach mice, none yet in people. 1 lab.

Mice: a single group. Cells, worms or flies and humans: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab
  • Animals1
  • In silico1

Effects

1

Left ventricular sympathetic fiber density

upin mice1

1 study

  1. SEMA3C increases left ventricular sympathetic fiber density in mice (shown by fibroblast-specific Sema3c knockout).

    “deleting fibroblast Sema3c lowered left ventricular sympathetic fiber density”

    Animalsshown by fibroblast-specific Sema3c knockoutleft ventricle

    A heart support cell group sustains nerves and pumping in mice

    AHA Scientific Sessions 2026 abstract

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 11 paper in 12 months
AHA Scientific Sessions 2026 Abstract

A heart support cell group sustains nerves and pumping in mice

Loss of the cell group reduced the share of blood pumped out of the left ventricle per beat from 84.0% to 68.8%.Loss of the cell group reduced the share of blood pumped out of the left ventricle per beat from 84.0% to 68.8%.

Mouse studyMechanisms
Paper

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