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Aging CellReview·12 h

Endothelial TLR4 at the Crossroads of Vascular Senescence and Targeted Senotherapeutics

Cellular senescence

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TLR41
VCAM11
TLR4 inhibitors1
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Declining chaperone-mediated autophagy prevents macrophages from clearing senescent cells with age

ResearchNature Aging and 1 more

University of Innsbruck links hydra senescence to falling taurine levels

ResearchPhys.org

Einstein researchers link chaperone-mediated autophagy decline to senescent cell accumulation

ResearchPR Newswire and 1 more

Trials

Registered6 Oct 2026

AKG and Brain Health in Aging

Phase 2 · University of Oklahoma

Registered2 Oct 2026

Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)

Phase 1 · Vinmec Research Institute of Stem Cell and Gene Technology

Registered1 Oct 2026

Functional Mobility and Resistance Exercise for Postmenopausal Females With Type 1 Diabetes

Institut de Recherches Cliniques de Montreal

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