RNASEH2A
- 1 lab in 1 country
- Funders: Foundation for Promotion of Cancer Research and 8 more
- Cells2
Effects
1Senescence-associated secretory phenotype (SASP)
downin human cells1
1 study
Senescence-associated secretory phenotype (SASP)
downin human cells1
RNASEH2A inhibits senescence-associated secretory phenotype (SASP) in human cells.
“induced the accumulation of nucleotide ligands and induction of certain tumourigenic SASP-like factors, promoting the metastatic properties of colorectal cancer cells.”
Cellsauxin-inducible degron mediated depletion in colorectal cancer cells
Communications biologyDec 28, 2022
Upstream
1Werner syndrome
downin human cells1
1 study
Werner syndrome
downin human cells1
Werner syndrome decreases RNASEH2A in human cells.
“and cells from individuals with Werner syndrome.”
CellsWerner syndrome
Communications biologyDec 28, 2022
Latest
bioRxiv
Incongruent end structures of leading and lagging telomeres dictate the nature of end replication problem
Preprint: experiments in cellsTelomerase and telomere maintenance
Communications Biology
RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells
Experiments in human cellsCellular senescence