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RAV1

Gene

2 papers2 findings

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Institute of General Medical Sciences and 1 more
  • Cells2

Effects

2

Lifespan

downin yeast cells1

1 study

  1. RAV1 shortens lifespan in yeast cells.

    “The RAVE complex promotes V-ATPase assembly and a rav1∆ mutant shortens replicative lifespan”

    Cellsrav1∆ mutant

    V-ATPase Disassembly at the Yeast Lysosome-Like Vacuole Is a Phenotypic Driver of Lysosome Dysfunction in Replicative Aging

    Aging cell16 Jan 2025

Replicative lifespan

downin yeast cells1

1 study

  1. RAV1 shortens replicative lifespan in yeast cells.

    “The RAVE complex promotes V-ATPase assembly and a rav1Δ mutant shortens replicative lifespan”

    Cellsin rav1Δ mutant

    V-ATPase Disassembly at the Yeast Lysosome-Like Vacuole Is a Phenotypic Driver of Lysosome Dysfunction in Replicative Aging

    bioRxiv : the preprint server for biology13 Dec 2024Preprint

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