Opa1
GeneMus musculus1 paper1 findingMGI 1921393NCBI Gene 74143Taxon 10090
- Animals1
Interventions
1INTERLEUKIN-17A
upin mouse cells1
1 study
INTERLEUKIN-17A
upin mouse cells1
INTERLEUKIN-17A increases Opa1 in mouse cells.
Cellschondrocyte
Interleukin-17A drives joint chondrocyte senescence through mitochondrial dysfunction in mice · Oral diseases · 30 Sep 2026
Latest
1AnimalsCellular senescence
Interleukin-17A drives joint chondrocyte senescence through mitochondrial dysfunction in mice
Blocking the cytokine with secukinumab reduced cartilage senescence and slowed osteoarthritis progression in a mouse model.