Nos3
GeneMus musculus1 paper2 findingsMGI 97362NCBI Gene 18127Taxon 10090
- Animals1
Interventions
1Intermittent fasting
upin mice1
1 study
Intermittent fasting
upin mice1
Intermittent fasting increases Nos3 in mice.
“ADF enhanced hepatocyte eNOS expression, and hepatocyte-specific eNOS knockout abolished the protective metabolic and anti-fibrotic effects of ADF.”
Animalsalternate-day fastinghepatocyte
Alternate-day fasting resolves liver fibrosis via hepatocyte eNOS signaling · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 27 Sep 2026
Effects
1Liver fibrosis
is required forin mice1
1 study
Liver fibrosis
is required forin mice1
Nos3 is required for liver fibrosis in mice.
“ADF enhanced hepatocyte eNOS expression, and hepatocyte-specific eNOS knockout abolished the protective metabolic and anti-fibrotic effects of ADF.”
Animalsfor alternate-day fasting-mediated protectionhepatocyte
Alternate-day fasting resolves liver fibrosis via hepatocyte eNOS signaling · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 27 Sep 2026
Latest
1Alternate-day fasting resolves liver fibrosis via hepatocyte eNOS signaling
Nitric oxide produced by hepatocytes during fasting blocks autophagy in stellate cells to halt fibrotic progression in mice.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) · Wang X et al.