MRPS5

2 papers1 finding

HGNC NCBI Gene Taxon

1 lab in 1 country

Funder: National Natural Science Foundation of China

Humans1
Model organisms1

Effects

1

Aged T cell phenotype

upin mice1

1 study

MRPS5 improves aged T cell phenotype in mice.
“overexpression of the mitoribosomal component Mrps5 reversed aged T cell phenotypes in a mouse model of viral infection or tumor”
Animalsviral infection or tumorT cell
Cryoelectron tomography reveals an age-related decline in mitoribosomes that contributes to T cell dysfunction in older individuals
Proceedings of the National Academy of Sciences of the United States of America29 Jul 2026

Latest

1 in 12 months

PNAS29 Jul

Cryoelectron tomography reveals an age-related decline in mitoribosomes that contributes to T cell dysfunction in older individuals

Study in peopleBlood and immune system

Nature23 May

Mitonuclear protein imbalance as a conserved longevity mechanism

Experiments in miceMechanisms