MPC2

There are 3 papers on MPC2 in aging research: none in people yet, 3 in animals. The newest story, Nov 9, 2026: “Blocking a fuel carrier may reduce kidney scarring in mice”.

Gene

3 papers study it1 finding

HGNCNCBI GeneTaxon

2 new papers in 30 daysSee all 3 papers on MPC2

At a glance

The findings reach mice, none yet in people. 1 lab; 3 trials.

Mice: a single group. Cells, worms or flies and humans: nothing yet.
  • 1 lab
  • 3 trials
  • 3 of 3 trials sponsored by developers of drugs aimed at it
  • Animals3

Effects

1

Fatty acid β-oxidation

downin mice1

1 study
  1. MPC2 inhibits fatty acid β-oxidation in mice (shown by kidney tubule-specific knockout).

    “Mpc2 CKO tubules had increased FAO by stable isotope tracer studies”

    Animalsshown by kidney tubule-specific knockoutkidney tubule

    Blocking a fuel carrier may reduce kidney scarring in mice

    AHA Scientific Sessions 2026 abstract

More on Fatty acid β-oxidation

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 1Nov 2026: 12 papers in 12 months
AHA Scientific Sessions 2026 Abstract

Blocking a fuel carrier may reduce kidney scarring in mice

In experiments with 22-month-old mice, a drug reduced kidney scarring and restored activity of genes involved in using fat for energy.In experiments with 22-month-old mice, a drug reduced kidney scarring and restored activity of genes involved in using fat for energy.

Mouse studyKidney