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MLF1

Gene

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Basic and Applied Basic Research Foundation of Guangdong Province and 8 more
  • Animals1

Effects

1

Cellular senescence

upin human cells1

1 study

  1. MLF1 induces cellular senescence in human cells.

    “silencing MLF1 suppressed H2O2-induced cell senescence while the phenotype was exacerbated by MLF1 overexpression”

    CellsH2O2-induced cell senescence in human AC16 cardiomyocytes

    Downregulation of MLF1 safeguards cardiomyocytes against senescence-associated chromatin opening

    Nucleic acids researchDec 11, 2024

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