MIR542
- 1 lab in 1 country
- Funders: National Natural Science Foundation of China and 2 more
- Humans1
- Animals1
Effects
2AMPK signalling
upin mouse cells1
1 study
AMPK signalling
upin mouse cells1
MIR542 activates AMPK signalling in mouse cells.
“suppressed Eef1a1 to activate the AMPK pathway, thereby improving mitochondrial function and attenuating cellular senescence”
Cellsskeletal muscle
Bioactive materials13 Jun 2026
Lipid accumulation
downin mouse cells1
1 study
Lipid accumulation
downin mouse cells1
MIR542 decreases lipid accumulation in mouse cells.
“miR-542-3p enriched in NMEVs directly targeted and downregulated Asxl2-PPARγ, leading to reduced lipid accumulation”
Cellsskeletal muscle
Bioactive materials13 Jun 2026
Latest
2 in 12 monthsActa Physiologica
Human Islet miR-199a-5p and miR-214-3p Associate With Donor Age, BMI, and Sex and Mediate Cellular Aging in Islet-Derived Cells
Cross-sectional study of 131 peopleMechanisms
Bioactive Materials
Neonatal muscle-derived extracellular vesicles containing miR-542-3p rejuvenate aged skeletal muscle via a functional microneedle patch
Experiments in miceMuscle