LONRF1

1. LONRF1 activates wnt/β-catenin signaling in mice.

   “whereas Lonrf1high/p16high fibroblasts showed activation of WNT (wingless and Int-1) signalling.”

   Animalsduring wound healing in Lonrf1high/p16high fibroblasts

   Transcriptomic characterization of Lonrf1 at the single-cell level under pathophysiological conditions

   Journal of biochemistry·Mar 9, 2023

More on Wnt/β-catenin signaling

1. LONRF1 activates NF-κB signaling in mice.

   “In normal and NASH (nonalcoholic steatohepatitis) liver, Lonrf1high LSECs showed activation of NF-kB and p53 pathways”

   Animalsin normal and NASH liverliver

   Transcriptomic characterization of Lonrf1 at the single-cell level under pathophysiological conditions

   Journal of biochemistry·Mar 9, 2023

More on NF-κB signaling

1. Age increases LONRF1 in mice.

   “Its expression in LSEC and Kupffer cells increased with age in the liver.”

   Animalswith ageliver

   Transcriptomic characterization of Lonrf1 at the single-cell level under pathophysiological conditions

   Journal of biochemistry·Mar 9, 2023