KCP

1. KCP inhibits apoptosis in mice.

   “KCP KO aggravated cardiac aging by increasing the levels of oxidative stress, inflammation, and cardiomyocyte apoptosis.”

   Animalsagingheart

   Kielin/chordin-like protein deficiency causes cardiac aging in male mice

   Journal of molecular medicine (Berlin, Germany)·May 6, 2023

More on Apoptosis

1. KCP inhibits oxidative stress and ROS signalling in mice.

   “KCP KO aggravated cardiac aging by increasing the levels of oxidative stress, inflammation, and cardiomyocyte apoptosis.”

   Animalsagingheart

   Kielin/chordin-like protein deficiency causes cardiac aging in male mice

   Journal of molecular medicine (Berlin, Germany)·May 6, 2023

More on Oxidative stress and ROS signalling

1. KCP inhibits cellular senescence in mice.

   “Furthermore, KCP KO increased the expression of cardiac senescence-related proteins in aged mice.”

   Animalsagingheart

   Kielin/chordin-like protein deficiency causes cardiac aging in male mice

   Journal of molecular medicine (Berlin, Germany)·May 6, 2023

More on Cellular senescence

1. KCP decreases cardiac remodeling in mice.

   “analysis of heart structure showed that KCP knockout (KO) aggravated cardiac remodeling in aged mice.”

   Animalsagingheartmales

   Kielin/chordin-like protein deficiency causes cardiac aging in male mice

   Journal of molecular medicine (Berlin, Germany)·May 6, 2023

1. KCP improves cardiac function in mice.

   “KCP KO aggravated aging-related cardiac dysfunction and remodeling in male mice.”

   Animalsagingheartmales

   Kielin/chordin-like protein deficiency causes cardiac aging in male mice

   Journal of molecular medicine (Berlin, Germany)·May 6, 2023