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Imp-L2

Gene

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab
  • Model organisms1

Effects

1

AKT/FOXO branch of insulin/IGF signaling

downin H. saltator1

1 study

  1. Imp-L2 inhibits AKT/FOXO branch of insulin/IGF signaling in H. saltator.

    “an anti-insulin (Imp-L2) lead to the downregulation of the AKT/FOXO branch of the IIS-signaling pathway in the fat body”

    Model organismsgamergates; together with reduced insulin receptor expressionfat body

    Insulin signaling and extended longevity in ants

    bioRxiv (Cold Spring Harbor Laboratory)29 Jun 2022Preprint

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