GREM1

2 papers1 finding

HGNC NCBI Gene Taxon

1 lab in 1 country

Funder: National Natural Science Foundation of China

Humans1
Animals1

Effects

1

Cellular senescence

upin human cells1

1 study

GREM1 induces cellular senescence in human cells.
“Cellular experiments demonstrated GREM1 overexpression suppressed trophoblast proliferation, migration, and invasion while inducing senescence, effects that were ameliorated by GREM1 knockdown.”
CellsGREM1 overexpression and knockdown experimentsHTR-8/SVneo trophoblast
Aberrant expression of Gremlin1 induces trophoblast senescence in the placenta of advanced maternal age pregnancy
Journal of translational medicine27 May 2026

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