F12

2 papers study it1 finding

HGNC NCBI Gene Taxon

1 lab in 1 country

Funders: Deutsche Forschungsgemeinschaft and 2 more

Animals1

Effects

1

Kidney injury

upin mice1

1 study

F12 increases kidney injury in mice.
“F12-deficient mice (F12-/-) are protected from hyperglycemia-induced kidney injury.”
Animalshyperglycemia-inducedkidney
Factor XII signaling via uPAR-integrin β1 axis promotes tubular senescence in diabetic kidney disease
Nature communicationsSep 11, 2024

Latest

1 paper in 12 months

Ageing Research ReviewsMay 31

Misplaced nucleic acids as a trigger of coagul-aging

ReviewMechanisms

Nature CommunicationsSep 12

Factor XII signaling via uPAR-integrin β1 axis promotes tubular senescence in diabetic kidney disease

Experiments in miceIntegrin signaling