Dsp1
- 1 lab in 1 country
- Funders: National Research Foundation and 1 more
- Model organisms1
Effects
5Tyrosine hydroxylase-positive neuron count
downin flies1
1 study
Tyrosine hydroxylase-positive neuron count
downin flies1
Dsp1 decreases tyrosine hydroxylase-positive neuron count in flies.
“Furthermore, these flies demonstrated neuromuscular junction (NMJ) defect, reduced eye size and a decrease in tyrosine hydroxylase (TH)-positive neurons, indicating neuronal toxicity induced by DSP1 overexpression.”
Model organismsneuronal-specific Dsp1 overexpressionneuron
Molecular brain13 Jul 2024
Eye size
downin flies1
1 study
Eye size
downin flies1
Dsp1 decreases eye size in flies.
“Furthermore, these flies demonstrated neuromuscular junction (NMJ) defect, reduced eye size and a decrease in tyrosine hydroxylase (TH)-positive neurons, indicating neuronal toxicity induced by DSP1 overexpression.”
Model organismsneuronal-specific Dsp1 overexpressioneye
Molecular brain13 Jul 2024
Neuromuscular junction defects
upin flies1
1 study
Neuromuscular junction defects
upin flies1
Dsp1 induces neuromuscular junction defects in flies.
“Furthermore, these flies demonstrated neuromuscular junction (NMJ) defect, reduced eye size and a decrease in tyrosine hydroxylase (TH)-positive neurons, indicating neuronal toxicity induced by DSP1 overexpression.”
Model organismsneuronal-specific Dsp1 overexpressionneuromuscular junction
Molecular brain13 Jul 2024
Lifespan
downin flies1
1 study
Lifespan
downin flies1
Dsp1 shortens lifespan in flies.
“We observed that climbing ability and life span are decreased in DSP1-overexpressed flies.”
Model organismsneuronal-specific Dsp1 overexpressionneuron
Molecular brain13 Jul 2024
Climbing ability
downin flies1
1 study
Climbing ability
downin flies1
Dsp1 impairs climbing ability in flies.
“We observed that climbing ability and life span are decreased in DSP1-overexpressed flies.”
Model organismsneuronal-specific Dsp1 overexpressionneuron
Molecular brain13 Jul 2024