Tyrosine hydroxylase-positive neuron count

1. Dsp1 decreases tyrosine hydroxylase-positive neuron count in flies.

   “Furthermore, these flies demonstrated neuromuscular junction (NMJ) defect, reduced eye size and a decrease in tyrosine hydroxylase (TH)-positive neurons, indicating neuronal toxicity induced by DSP1 overexpression.”

   Model organismsneuronal-specific Dsp1 overexpressionneuron

   The overexpression of DSP1 in neurons induces neuronal dysfunction and neurodegeneration phenotypes in Drosophila

   Molecular brain·13 Jul 2024

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