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clh-1

Gene

2 papers study it1 finding

NCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Institute of Neurological Disorders and Stroke and 1 more
  • Model organisms2

Effects

1

Neuronal damage

upin worms1

1 study

  1. clh-1 increases neuronal damage in worms.

    “loss of clh-1 extends life span, improves stress resistance, reduces neuronal damage, and extends health span.”

    Model organismsshown by loss of clh-1

    The loss of a ClC anion channel increases life span, health span, and stress resistance by alkalinizing a pair of glial cells in C. elegans

    Science advances

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