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CIRCKIF18A

Gene

1 paper studies it1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Key Research and Development Program of Zhejiang Province and 1 more
  • Animals1

Effects

1

Cellular senescence

downin rat cells1

1 study

  1. CIRCKIF18A decreases cellular senescence in rat cells.

    “circKIF18A was downregulated in IVDD and attenuated senescent phenotypes such as cell cycle arrest and extracellular matrix degradation in NPCs.”

    Cellsin NPCs

    Oxidative stress-induced circKIF18A downregulation impairs MCM7-mediated anti-senescence in intervertebral disc degeneration

    Experimental & molecular medicine

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