argk-1

1. argk-1 is required for lifespan in worms.

   “argk-1 RNAi or daf-16 mutant nullified the longevity”

   Model organismsTM-induced longevity

   Superoxide signal orchestrates tetrathiomolybdate-induced longevity via ARGK-1 in Caenorhabditis elegans

   Free radical biology & medicine·Jul 16, 2024

2. argk-1 extends lifespan in worms.

   “overexpression of ARGK-1 extends C. elegans lifespan”

   Model organismsoverexpression

   C. elegans S6K Mutants Require a Creatine-Kinase-like Effector for Lifespan Extension

   Cell reports·Feb 25, 2016

1. argk-1 is required for stress resistance in worms.

   “argk-1 is also required for the reduced body size and increased stress resistance observed in rsks-1/S6K mutants”

   Model organismsin rsks-1/S6K mutants

   C. elegans S6K Mutants Require a Creatine-Kinase-like Effector for Lifespan Extension

   Cell reports·Feb 25, 2016

1. argk-1 activates AMPK signalling in worms.

   “overexpression of ARGK-1 extends C. elegans lifespan, in part by activating the energy sensor AAK-2/AMPK”

   Model organismsby ARGK-1 overexpression

   C. elegans S6K Mutants Require a Creatine-Kinase-like Effector for Lifespan Extension

   Cell reports·Feb 25, 2016

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