ACS1

1. ACS1 is required for beta-hydroxybutyrate in yeast cells.

   “In addition, we identify mitochondrial acetyl-CoA metabolism (ACS1) and mtFAS pathways to be critical for βHB enrichment during CR.”

   Cellsduring CR

   Exploring Acetyl-CoA-Mediated Beta-Hydroxybutyrate Enrichment in Yeast: A Mechanistic Link to Longevity · GSA 2025 abstract · 31 Dec 2025

Beta-hydroxybutyrate →