Exploring Acetyl-CoA-Mediated Beta-Hydroxybutyrate Enrichment in Yeast: A Mechanistic Link to Longevity

Abstract

Aging predisposes organisms to diseases ranging from diabetes to Alzheimer’s, driving interest in interventions like Caloric Restriction (CR), which extends lifespan across species. While CR’s benefits are well-documented, its metabolic mechanisms remain incompletely understood.