1 paper2 findings
Antiseizure medications
upin humans1OR 1.44
Antiseizure medications are associated with young-onset dementia in humans (Adjusted OR 1.44, 95% CI 1.36–1.52).
“27.3% vs 10.3% had ASM dispensations (adjusted OR 1.44, 95% CI 1.36-1.52).”
HumansFrench nested case-control analysis; medication dispensationsUp to 10 years before index date
Epilepsy linked to dementia diagnosed before age 65
Neurology14 Oct 2026
Epilepsy
upin humans1OR 3.76
Epilepsy is associated with young-onset dementia in humans (Adjusted OR 3.76, 95% CI 3.42–4.14).
“In France, 12.5% of YOD cases vs 1.2% of controls had previous epilepsy-related codes (adjusted OR 3.76, 95% CI 3.42-4.14)”
HumansFrench nested case-control analysis; previous epilepsy-related codesUp to 10 years before index date
Epilepsy linked to dementia diagnosed before age 65
Neurology14 Oct 2026
Massachusetts General Hospital
1 trial388 people
In a French cohort, dementia before 65 developed in 2.20% with newly diagnosed epilepsy versus 0.21% without epilepsy over 10 years.In a French cohort, dementia before 65 developed in 2.20% with newly diagnosed epilepsy versus 0.21% without epilepsy over 10 years.