Type 2 diabetic nephropathy

1 paper

Model organisms1

Trial sponsors

Pfizer
Company1 trialPhase 16 people

Latest

1 in 12 months

Biological ResearchJun 3

From in vitro to in vivo: hypoxia attenuates replicative senescence and preserves therapeutic activity in long-term passaged human umbilical cord-derived mesenchymal stem cells

Experiments in miceInterventions

FASEB JournalMay 19

A Novel Role of Adipokine 'Intelectin-1': Ameliorating Renal Fibrosis Through Inhibition of Renal Tubular Epithelial Cell Senescence

Experiments in miceRenal fibrosis

JCI InsightNov 26

Role of cGAS/STING pathway in aging and sexual dimorphism in diabetic kidney disease

Study in peoplecGAS–STING signalling

Disease Models & MechanismsApr 11

Promoting mitochondrial dynamics by inhibiting the PINK1-PRKN pathway to relieve diabetic nephropathy

Experiments in fliesMitochondrial fission and fusion

Redox BiologyMar 26

The redox-sensitive GSK3β is a key regulator of glomerular podocyte injury in type 2 diabetic kidney disease

Experiments in miceKidney

GeroScienceJun 30

Renoprotective effects of empagliflozin in type 1 and type 2 models of diabetic nephropathy superimposed with hypertension

Experiments in ratsEmpagliflozin

American Journal of Physiology Renal PhysiologyOct 1

Progression of diabetic kidney disease in T2DN rats

Experiments in animalsMechanisms

Experimental Diabetes ResearchSep 22

Dietary restriction ameliorates diabetic nephropathy through anti-inflammatory effects and regulation of the autophagy via restoration of Sirt1 in diabetic Wistar fatty (fa/fa) rats: a model of type 2 diabetes

Experiments in ratsDietary restriction