Testicular aging

2 papers

Animals1

Latest

14 in 12 months

Ageing Research Reviews27 Mar

Testicular aging revisited: Current understanding of mechanisms and emerging interventions

ReviewMechanisms

Biology Direct26 Mar

SIRT1 haploinsufficiency recapitulates age-associated subfertility through sperm α-tubulin hyperacetylation

Experiments in miceSirtuin signalling

Andrology13 Mar

Testicular SIRT1 Loss Reveals an Aging-Like Proteomic Landscape and Precipitates Reproductive Deterioration

Experiments in miceSirtuin signalling

Journal of Molecular Cell Biology9 Mar

Integrated single-nucleus transcriptomic and chromatin accessibility analysis reveals key molecular basis of human testicular aging

Cross-sectional study in peopleMechanisms

Biogerontology5 Feb

Sertoli cell aging: damage accumulation and epigenetic alterations affecting male fertility

ReviewReproductive system

Annals of Medicine4 Feb

Testicular ageing as a central hallmark of male senescence: characteristics, molecular mechanisms and emerging therapeutic strategies

ReviewCellular senescence

GeroScience31 Jan

Single-cell immune atlas of mouse testes unveils metabolic reprogramming of FOLR2 + macrophages in orchestrating testicular immunity during aging

Experiments in 6,622 miceOxidative phosphorylation

Insect Molecular Biology29 Jan

LncRNA:CR43306 modulates testicular aging via cell adhesion in Drosophila

Experiments in fliesMechanisms

Cells28 Jan

When Testosterone Fades: Leydig Cell Aging Shaped by Environmental Toxicants, Metabolic Dysfunction, and Testicular Niche Crosstalk

ReviewAutophagy

Journal of Endocrinological Investigation9 Jan

Caloric restriction attenuates oxidative and inflammatory markers of aging, while compromising germinative epithelium homeostasis in the rat aged testis

Experiments in 14 ratsDietary restriction