Stressful life events are associated with stress-related disorders in humans (HR 1.62, 95% CI 1.58–1.67).
“The number of different life events was associated with a higher risk of stress-related (hazard ratio [HR], 1.62; 95% confidence interval [CI], 1.58-1.67)”
Stress-related disorders are associated with incident stroke in humans (Stress-related disorders only versus neither disorder group; fully adjusted model) (HR 1.24, 95% CI 1.19-1.30).
“In the fully adjusted model, stroke risk was elevated for stress-only (HR 1.24; 95% CI 1.19-1.30)”
HumansStress-related disorders only versus neither disorder group; fully adjusted modelUp to 4 years
More types of recorded events were linked to stress-related disorders, with a hazard ratio of 1.62, and to anxiety, depression, other illnesses and frailty.More types of recorded events were linked to stress-related disorders, with a hazard ratio of 1.62, and to anxiety, depression, other illnesses and frailty.
Adults with both kinds of disorders had a stroke hazard ratio—a measure of relative risk—of 1.33 compared with those with neither.Adults with both kinds of disorders had a stroke hazard ratio—a measure of relative risk—of 1.33 compared with those with neither.
During follow-up from 2018 through 2023, dementia occurred in 6.8% of adults with both disorder types versus 2.3% with neither.During follow-up from 2018 through 2023, dementia occurred in 6.8% of adults with both disorder types versus 2.3% with neither.