Spontaneous tumorigenesis
2 papers2 findings
- Animals2
Interventions
1Constant light
upin rats1
1 study
Constant light
upin rats1
Constant light increases spontaneous tumorigenesis in rats.
“exposure to NL and LL regimens accelerated development of metabolic syndrome and spontaneous tumorigenesis”
Animalscompared to the standard LD regimen
Circadian disruption induced by light-at-night accelerates aging and promotes tumorigenesis in rats
Aging2 Oct 2009
Upstream
1BECN1
downin mice1
1 study
BECN1
downin mice1
BECN1 decreases spontaneous tumorigenesis in mice.
“spontaneous tumorigenesis are diminished.”
Animalsin Becn1 F121A/F121A knock-in mice
Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice
Nature30 May 2018
Latest
Cancer Research
Phosphorylation Control of p53 DNA-Binding Cooperativity Balances Tumorigenesis and Aging
Experiments in miceTP53
Current Aging Science
Light-at-night-induced circadian disruption, cancer and aging
Experiments in ratsCancer
Cell Cycle
Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice
Experiments in micemTOR inhibitors
Laboratory Investigation; a Journal of Technical Methods and Pathology
Combined loss of p21(waf1/cip1) and p27(kip1) enhances tumorigenesis in mice
Experiments in miceCDKN1A