Cells·Apr 27Astro-Versus Microglia-Enriched Transcriptomes from Aged Atxn2-CAG100-Knockin Mice Suggest Underlying Pathology of RNA Processing at Ribosomes, and Possibly at U-BodiesExperiments in miceMechanismsPaper
Cell Reports·Dec 21Repeat-associated non-AUG translation as a common mechanism for the polyGln ataxiasStudy in peopleMechanismsPaper
Annals of Neurology·Sep 25Staufen Impairs Autophagy in NeurodegenerationExperiments in miceAutophagyPaper
eLife·Feb 16Endurance exercise ameliorates phenotypes in Drosophila models of spinocerebellar ataxiasExperiments in fliesEndurance exercisePaper
Communications Biology·Nov 13Conserved Pbp1/Ataxin-2 regulates retrotransposon activity and connects polyglutamine expansion-driven protein aggregation to lifespan-controlling rDNA repeatsExperiments in cellsTransposable element activityPaper