Spinocerebellar ataxia type 2

Papers on spinocerebellar ataxia type 2

9 papers

Monday, April 27

CellsApr 27

Astro-Versus Microglia-Enriched Transcriptomes from Aged Atxn2-CAG100-Knockin Mice Suggest Underlying Pathology of RNA Processing at Ribosomes, and Possibly at U-Bodies

Experiments in miceMechanisms

Sunday, December 21

Cell ReportsDec 21

Repeat-associated non-AUG translation as a common mechanism for the polyGln ataxias

Study in peopleMechanisms

Saturday, October 15

International Journal of Molecular SciencesOct 15

Mutant Ataxin-2 Expression in Aged Animals Aggravates Neuropathological Features Associated with Spinocerebellar Ataxia Type 2

Experiments in animalsMechanisms

Sunday, September 25

Annals of NeurologySep 25

Staufen Impairs Autophagy in Neurodegeneration

Experiments in miceAutophagy

Wednesday, February 16

eLifeFeb 16

Endurance exercise ameliorates phenotypes in Drosophila models of spinocerebellar ataxias

Experiments in fliesEndurance exercise

Monday, April 8

Movement DisordersApr 8

Neurorehabilitation Improves the Motor Features in Prodromal SCA2: A Randomized, Controlled Trial

Trial in peopleInterventions

Tuesday, November 13

Communications BiologyNov 13

Conserved Pbp1/Ataxin-2 regulates retrotransposon activity and connects polyglutamine expansion-driven protein aggregation to lifespan-controlling rDNA repeats

Experiments in cellsTransposable element activity

Wednesday, August 22

Movement DisordersAug 22

Neurorehabilitation therapy in spinocerebellar ataxia type 2: A 24-week, rater-blinded, randomized, controlled trial

Trial in peopleInterventions

Friday, June 8

CerebellumJun 8

In Vivo Analysis of the Climbing Fiber-Purkinje Cell Circuit in SCA2-58Q Transgenic Mouse Model

Experiments in animalsMechanisms