Degenerative spine disease

Disease

2 papers1 finding

Humans2

Associations

Telomere length

downin humans1HR 0.953

1 study

Telomere length is associated with degenerative spine disease in humans (HR=0.953).
“Observationally, longer TL was associated with lower risk of any degenerative spine disease (HR=0.953, p<0.001)”
HumansEuropean ancestry; no baseline degenerative spine disease; longer telomere lengthleukocyten = 265,805
Longer telomeres linked to lower spine disease risk
World neurosurgery12 Oct 2026

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World Neurosurgery3 h

Longer telomeres linked to lower spine disease risk

In 265,805 people, longer telomeres were linked to lower rates of new spine diagnoses; the hazard ratio, comparing rates over time, was 0.953.In 265,805 people, longer telomeres were linked to lower rates of new spine diagnoses; the hazard ratio, comparing rates over time, was 0.953.

Mendelian randomisation in 265,805 peoplePopulations

Paper

BMC Musculoskeletal Disorders2 Oct

Comparative analysis of surgically treated degenerative cervical and lumbar spine diseases using multiple clinical aging indices

Cohort study of 313 peoplePopulations