Progeroid phenotype

1 paper

Animals1

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Science29 Jan

DNA-protein cross-links promote cGAS-STING-driven premature aging and embryonic lethality

Experiments in micecGAS–STING signalling

Biogerontology13 Oct

POLR3A mutations cause nucleolus abnormalities and aberrant telomerase RNA metabolism in induced pluripotent stem cells from Wiedemann-Rautenstrauch premature aging syndrome patient

Experiments in human cellsTelomerase and telomere maintenance

Redox Biology21 Jul

Sirt2 ablation exacerbates Sod1 knockout-induced progeroid phenotype in mice

Experiments in miceSOD1