Photoreceptor degeneration

Disease

2 papers study it16 more mention it1 finding

Animals2

Interventions

Nicotinamide mononucleotide

downin mice1

1 study

Nicotinamide mononucleotide protects against photoreceptor degeneration in mice.
“preservation of the outer nuclear layer (ONL) thickness”
Animalsafter retinal detachment
Neuroprotective effects and mechanisms of action of nicotinamide mononucleotide (NMN) in a photoreceptor degenerative model of retinal detachment
AgingDec 29, 2020

Latest

5 papers in 12 months

Taiwan Journal of OphthalmologyOct 15

Regenerative therapies using pluripotent stem cell-derived retinal organoids

ReviewEye

Paper

Methods in Molecular BiologySep 2

Retinal Degeneration and Regeneration in Xenopus laevis Tadpoles

Experiments in frogsEye

Paper

PLOS OneAug 20

Generation of dual mouse models of retinal degeneration with slow and rapid progression driven by ectopic RIP3 expression

Experiments in miceEye

Paper

PNASMay 11

Chaperone-mediated autophagy protects against retinal photoreceptor degeneration by modulating proteostasis of glucose metabolism enzymes

Experiments in miceEye

Paper

AntioxidantsMar 28

Oxidative Stress Signaling and Regenerative Responses in a Larval Zebrafish Model of Retinal Light Damage

Experiments in zebrafishOxidative stress and ROS signaling

Paper

PLOS OneMar 9

Evaluation of risk promoting effects for age-related macular degeneration by estradiol

Experiments in ratsEye

Paper

Cell Death & DiseaseAug 9

Age-related retinal degeneration resulting from the deletion of Shp2 tyrosine phosphatase in photoreceptor neurons

Experiments in miceEye

Paper

OphthalmologyFeb 13

Photoreceptor Layer Thinning Is an Early Biomarker for Age-Related Macular Degeneration: Epidemiologic and Genetic Evidence from UK Biobank OCT Data

Cohort study in peopleAge-related macular degeneration

Paper

Redox BiologyFeb 8

REV-ERBα regulates age-related and oxidative stress-induced degeneration in retinal pigment epithelium via NRF2

Experiments in miceNRF2–KEAP1 antioxidant response

Paper

Disease Models & MechanismsDec 17

A protein-trap allele reveals roles for Drosophila ATF4 in photoreceptor degeneration, oogenesis and wing development

Experiments in model organismsMechanisms

Paper