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Periprosthetic osteolysis

There are 3 papers on periprosthetic osteolysis in aging research: none in people yet, 3 in animals.

Disease

3 papers study it2 more mention it2 findings

See all 5 papers on periprosthetic osteolysis

  • Animals3

Interventions

2

Ruxolitinib

downin mice1

1 study

  1. Ruxolitinib protects against periprosthetic osteolysis in mice.

    “addition of the JAK inhibitor ruxolitinib restored the response of lymphatic vessels to external stimuli in aged mice to protect against osteolysis progression”

    Animals

    Preventing periprosthetic osteolysis in aging populations through lymphatic activation and stem cell-associated secretory phenotype inhibition

    Communications biology

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Vegf-c

downin mice1

1 study

  1. Vegf-c prevents periprosthetic osteolysis in mice (caused by titanium alloy particles or inflammatory cytokines LPS/TNF-α).

    “we counteracted excessive differentiation of osteoclasts and osteolysis caused by titanium alloy particles or inflammatory cytokines LPS/TNF-α”

    Animalscaused by titanium alloy particles or inflammatory cytokines LPS/TNF-α

    Preventing periprosthetic osteolysis in aging populations through lymphatic activation and stem cell-associated secretory phenotype inhibition

    Communications biology

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