Ovarian defects

1. Engineered fsh decreases ovarian defects in mice.

   “FSH released from the LH secretory pathway rescued ovarian defects in Fshb-null mice as efficiently as constitutively secreted FSH.”

   Animalsin Fshb-null miceovaryfemales

   Redirecting intracellular trafficking and the secretion pattern of FSH dramatically enhances ovarian function in mice

   Proceedings of the National Academy of Sciences of the United States of America·31 Mar 2014

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