Long-term obesity

1. Long-term obesity is associated with IL-6 in humans (Log IL-6: 0.69 vs 1.03 vs 0.99; Cohen f = 0.53 (95% CI, 0.41–0.62)).

   “IL-6 (log, 0.69 [0.5] vs 1.03 [0.4] vs 0.99 [0.4]; P < .001; f = 0.53 [95% CI, 0.41-0.62])”

   HumansHealthy BMI across life versus persistent obesity since adolescence versus persistent obesity since childhoodn = 205

   Long-Term Obesity and Biological Aging in Young Adults

   JAMA network open·1 Jul 2025

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1. Long-term obesity is associated with C-reactive protein in humans (1.69 vs 3.67 vs 4.24 mg/L; Cohen f = 0.57 (95% CI, 0.44–0.70)).

   “including mean (SD) hs-CRP (1.69 [2.1] vs 3.67 vs 4.24 [2.4] mg/L; P < .001; f = 0.57 [95% CI, 0.44-0.70])”

   HumansHealthy BMI across life versus persistent obesity since adolescence versus persistent obesity since childhoodn = 205

   Long-Term Obesity and Biological Aging in Young Adults

   JAMA network open·1 Jul 2025

More on C-reactive protein