Papers on instability

2,399 papers78 new in 30 days

Thursday, October 29

Journal of DentistryOct 29

SHED in Regenerative Medicine: Cell-Based Therapies and Cell-Free Strategies

ReviewInterventions

Paper

Biomaterials AdvancesOct 29

Ultrasound-triggered bio-scaffold integrating engineered stem cells for cartilage regeneration

Experiments in ratsUltrasound

Paper

Wednesday, October 28

Frontiers in PsychologyOct 28

Effects of exercise on balance in people with Parkinson's disease: an umbrella review of systematic reviews and meta-analyses of randomized controlled trials

PRISMA 2020 flow diagram (databases and registers).

Systematic review of randomized trialsAquatic exercise

Paper

BMC GeriatricsOct 28

Machine learning-based fall risk prediction in community-dwelling older adults using dual-task spatiotemporal gait parameters

Case-control study of 209 peopleBiomarkers

Paper

Tuesday, October 27

GenesOct 27

Diagnostic and Clinical Considerations in Myeloid Neoplasms with del(5q): Distinguishing Myelodysplastic Neoplasm with Low Blasts and del(5q) from Myeloid Neoplasms with del(5q) Post-Cytotoxic Therapy

Hypolobated/monolobated megakaryocytes (white arrows) in MDS-5q.

ReviewMechanisms

Paper

NutrientsOct 27

The Gut Microbiome-Estrogen Axis in Menopause: Implications for Body Composition, Cardiometabolic Health and Nutrition

Proposed conceptual framework linking menopause, the estrobolome, gut microbiome remodeling, and microbiome-mediated metabolic aging.

ReviewMicrobiome composition

Paper

International Journal of Molecular SciencesOct 27

Cellular Senescence in Ocular Surface Diseases: Molecular Mechanisms and Therapeutic Perspectives

Integrated framework of stress-induced cellular senescence and SASP-mediated ocular surface pathology.

ReviewCellular senescence

Paper

Brain InformaticsOct 27

STABLE-BAG: a stability-aware framework for SHAP-based brain age gap decomposition

Computational studyAI & data

Paper

Monday, October 26

ESC Congress 2026 AbstractOct 26

Alzheimer’s blood marker linked to standing blood pressure drops

In a 15-year study of 1,492 older adults, an elevated Alzheimer’s-related blood marker tracked with progressively larger blood pressure drops upon standing.In a 15-year study of 1,492 older adults, an elevated Alzheimer’s-related blood marker tracked with progressively larger blood pressure drops upon standing.

Blood samples contain sparse versus dense dark protein fragments among blood cells, beside standing groups wearing blood pressure cuffs.

Cohort · 1,492 peoplePopulations

Paper

ESC Congress 2026 AbstractOct 26

Aortic plaque characteristics and hypertension: insights from non-obstructive general angioscopy

Cross-sectional study of 432 peopleHypertension

Paper

ESC Congress 2026 AbstractOct 26

Validation of a wrist-worn dual-sensor applanation tonometry device for blood pressure measurement under rest and stress conditions

Study of 25 peopleDiastolic blood pressure

Paper

ESC Congress 2026 AbstractOct 26

Loss of chromosome Y in elderly men is not associated with cardiovascular risk following acute myocardial infarction

Cohort study of 709 peopleAcute myocardial infarction

Paper

European Review of Aging and Physical ActivityOct 26

Effect of 12-week unstable surfaces resistance training on muscle stiffness, muscle co-activation, and balance in older individuals

Randomized trial in 46 peopleMuscle

Paper

ESC Congress 2026 AbstractOct 26

Silicon carbide nanowires preserve human atrial microtissue function and show a preliminary reduction of AF duration in an aged-rat atrial tachypacing model

Experiments in ratsInterventions

Paper

ESC Congress 2026 AbstractOct 26

Magnetic particle imaging of macrophage phagocytosis evaluates plaque vulnerability and therapeutic efficacy in atherosclerosis

Experiments in miceAtherosclerosis

Paper

Biochemistry BiokhimiiaOct 26

Accelerated Senescence of Fibroblast-Like Cells Derived from Induced Pluripotent Stem Cells of a Patient with Wiedemann-Rautenstrauch Progeroid Syndrome

Experiments in human cellsCellular senescence

Paper

BMC Medical Research MethodologyOct 26

Investigating the instability of variable selection in Lasso-penalized Cox proportional hazards models: a simulation study on low-dimensional real-world medical data

Computational studyBiomarkers

Paper

Sunday, October 25

Regenerative BiomaterialsOct 25

Wnt-activated osteocyte-driven 3D-bioprinted scaffolds orchestrate bone remodeling, angiogenesis and innervation to accelerate critical bone defect repair

Experiments in miceBones and joints

Paper

Current Sleep Medicine ReportsOct 25

Biological Mechanisms Underlying the Adverse Health Consequences of Human Circadian Misalignment from Night Shift Work

Simulated shift work study in humans revealing increased DNA damage after circadian misalignment due to simulated night shift.

ReviewMechanisms

Paper

Saturday, October 24

Clinical Colorectal CancerOct 24

Early-Onset Colorectal Cancer: Epidemiology, Etiologic Pathways, and Emerging Prevention Strategies

ReviewEarly-onset colorectal cancer

Paper

Journal of Oral RehabilitationOct 24

Association Between Edentulism and Postural Stability Among Middle-Aged and Older Adults: A Nationwide Cross-Sectional Study

Cross-sectional study of 13,047 peopleEdentulism

Paper

Ageing Research ReviewsOct 24

Neurodegeneration in Sub-Saharan Africa: Intersections of Biological Ageing, Genomic Diversity and the Lifetime Exposome

ReviewMechanisms

Paper

Friday, October 23

BiomacromoleculesOct 23

Cell Cryoisolation and Cryopreservation without Any Organic Solvent

Experiments in cellsInterventions

Paper

Pharmacology & TherapeuticsOct 23

Navigating the landscape of stem cell therapeutics: Overcoming translational hurdles via emerging technologies and regulatory frontiers

ReviewInterventions

Paper

Current Opinion in Genetics & DevelopmentOct 23

Beyond inherited repeat length: somatic expansions in Huntington disease

ReviewMechanisms

Paper

Wednesday, October 21

bioRxivOct 21

Weaker navigation signals may reflect instability in older adults

An observational study using virtual navigation and brain scans in 85 older adults linked steadier directional activity patterns to stronger signals.An observational study using virtual navigation and brain scans in 85 older adults linked steadier directional activity patterns to stronger signals.

Brain tissue with branching neurons surrounds orderly clusters in blue-green patches and irregular clusters in gray patches, with a dark neuron at the center.

Preprint: cross-sectional · 85 peopleMechanisms

Paper

Kardiovaskulyarnaya Terapiya I ProfilaktikaOct 21

Mechanisms of brain aging. A review: Part I

ReviewMechanisms

Paper

Journal of the American Geriatrics SocietyOct 21

Re-Evaluating Predictive Performance in the Clinical Risk Analysis Index of Frailty

Cohort study of 410,715 peopleBiomarkers

Paper

Tuesday, October 20

bioRxivOct 20

Protein helped limit calcium buildup in mouse arteries

Experiments in 18-month-old mice found faster atherosclerosis and arterial calcium buildup when the gene-regulating protein Rev-erb was absent.Experiments in 18-month-old mice found faster atherosclerosis and arterial calcium buildup when the gene-regulating protein Rev-erb was absent.

Artery cross-sections beside mice show thick plaque with clustered calcium deposits compared with a thinner wall, little plaque, and a wider opening.

Preprint: mouse studyMechanisms

Paper

The Journals of Gerontology, Series BOct 20

Driving changes linked to later cognitive decline in older adults

A driving-based model detected 19 of 25 older adults who developed sustained mild cognitive impairment, with a median lead time of 18 months.A driving-based model detected 19 of 25 older adults who developed sustained mild cognitive impairment, with a median lead time of 18 months.

Cars of different sizes sit beside upright, faceless people, surrounded by winding roads with different bends, scattered houses, and trees.

Cohort · 298 peopleBiomarkers

Paper