Immune thrombocytopenia
1 paper3 findings
- Humans1
Associations
3CD21-CD24- and CD21-CD24++ naïve and memory IgMD+ B-cell populations
upin humans1
1 study
CD21-CD24- and CD21-CD24++ naïve and memory IgMD+ B-cell populations
upin humans1
Immune thrombocytopenia is associated with CD21-CD24- and CD21-CD24++ naïve and memory IgMD+ B-cell populations in humans.
“Patients with ITP>65 had expanded CD21-CD24- and CD21-CD24++ naïve and memory IgMD+ B-cell populations compared to the HC>65 group.”
Humanscompared with age-matched healthy controlsblood
Frontiers in immunology12 May 2026
More on CD21-CD24- and CD21-CD24++ naïve and memory IgMD+ B-cell populations
CD21-CD24- naïve B-cell population
upin humans1
1 study
CD21-CD24- naïve B-cell population
upin humans1
Immune thrombocytopenia is associated with CD21-CD24- naïve B-cell population in humans.
“patients with ITP had a lower B-cell count, but a significant increase in the CD21-CD24- naïve B-cell subset.”
Humanscompared with age-matched healthy controlsblood
Frontiers in immunology12 May 2026
B-cell count
downin humans1
1 study
B-cell count
downin humans1
Immune thrombocytopenia is associated with B-cell count in humans.
“Comparison of the ITP ≤ 65 group with the HC ≤ 65 group showed that patients with ITP had a lower B-cell count”
Humanscompared with age-matched healthy controlsblood
Frontiers in immunology12 May 2026
Trial sponsors
Novartis Pharmaceuticals Corporation
Company1 trialPhase 226 people
China Immunotech (Beijing) Biotechnology
Company1 trialPhase 12 people
10 trialsPhase 4906 people
Fujian Medical University Union Hospital
1 trialPhase 4608 people
Peking University People's Hospital
20 trialsPhase 32,468 people
Assistance Publique - Hôpitaux de Paris
1 trialPhase 3272 people
University Hospitals Bristol and Weston NHS Foundation Trust
1 trialPhase 3123 people
Chinese SLE Treatment And Research Group
1 trialPhase 2/3164 people