CD21-CD24- naïve B-cell population

1. Immune thrombocytopenia is associated with CD21-CD24- naïve B-cell population in humans.

   “patients with ITP had a lower B-cell count, but a significant increase in the CD21-CD24- naïve B-cell subset.”

   Humanscompared with age-matched healthy controlsblood

   Age-related and disease-specific changes in B-cell profiles in older adults with immune thrombocytopenia

   Frontiers in immunology·12 May 2026

More on Immune thrombocytopenia

1. Older age is associated with CD21-CD24- naïve B-cell population in humans.

   “Patients with ITP>65, compared with those ≤65, showed reduced immature/transitional B cell subsets, an increased population of CD21-CD24- naïve B cells”

   Humansimmune thrombocytopeniablood

   Age-related and disease-specific changes in B-cell profiles in older adults with immune thrombocytopenia

   Frontiers in immunology·12 May 2026