CD21-CD24- and CD21-CD24++ naïve and memory IgMD+ B-cell populations

1. Immune thrombocytopenia is associated with CD21-CD24- and CD21-CD24++ naïve and memory IgMD+ B-cell populations in humans.

   “Patients with ITP>65 had expanded CD21-CD24- and CD21-CD24++ naïve and memory IgMD+ B-cell populations compared to the HC>65 group.”

   Humanscompared with age-matched healthy controlsblood

   Age-related and disease-specific changes in B-cell profiles in older adults with immune thrombocytopenia

   Frontiers in immunology·12 May 2026

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