Hyperammonemia

1 paper1 finding

Animals1

Effects

1

Cerebrovascular density

downin rats1

1 study

Hyperammonemia decreases cerebrovascular density in rats.
“Reduction in cerebrovascular density in hyperammonemia-induced rats, similar to that seen in 12-month-old rats, using von Willebrand factor staining, was observed.”
Animalshyperammonemia-inducedbrain
Unraveling Ammonia-Induced Brain Endothelial Senescence: Role of miRNA-183-5p
Antioxidants & redox signaling23 May 2025

Latest

Antioxidants & Redox Signaling23 May

Unraveling Ammonia-Induced Brain Endothelial Senescence: Role of miRNA-183-5p

Experiments in ratsCellular senescence

Nature Communications31 Dec

A high-protein diet-responsive gut hormone regulates behavioral and metabolic optimization in Drosophila melanogaster

Experiments in fliesGut and microbiome

The Journal of Nutritional Biochemistry24 Oct

L-Isoleucine reverses hyperammonemia-induced myotube mitochondrial dysfunction and post-mitotic senescence

Experiments in cellsInterventions

Aging Cell27 Apr

Dysregulated cellular redox status during hyperammonemia causes mitochondrial dysfunction and senescence by inhibiting sirtuin-mediated deacetylation

Study in peopleMechanisms

Human Molecular Genetics6 Mar

Nicotinamide riboside rescues dysregulated glycolysis and fatty acid β-oxidation in a human hepatic cell model of citrin deficiency

Experiments in cellsInterventions

Ageing Research Reviews18 Jul

Non-alcoholic fatty liver disease-related fibrosis and sarcopenia: An altered liver-muscle crosstalk leading to increased mortality risk

ReviewMechanisms