What does the research say about HIV persistence?

HIV persistence

There is 1 paper on HIV persistence in aging research: 1 observational study in people.

1 paper studies it6 more mention it1 finding

1 new paper in 30 daysSee all 7

“peripheral blood leukocytes from these subjects have enhanced expression of a network of genes regulated by cellular senescence driving transcription factors (TFs) FOXO3, SMAD2 and IRF3”

Microbiome and Metabolome driven differentiation of TGF-β producing Tregs leads to Senescence and HIV latencybioRxiv (Cold Spring Harbor Laboratory)2020doi:10.1101/2020.12.15.422949

Humans1

Associations

Cellular senescence

upin humans1

1 study

Cellular senescence is associated with HIV persistence in humans (ART-treated immunologic non-responders with poor CD4 T-cell reconstitution).
“peripheral blood leukocytes from these subjects have enhanced expression of a network of genes regulated by cellular senescence driving transcription factors (TFs) FOXO3, SMAD2 and IRF3”
HumansART-treated immunologic non-responders with poor CD4 T-cell reconstitutionperipheral blood leukocytes
Microbiome and Metabolome driven differentiation of TGF-β producing Tregs leads to Senescence and HIV latency
bioRxiv (Cold Spring Harbor Laboratory)Dec 15, 2020Preprint