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Frozen shoulder

There are 3 papers on frozen shoulder in aging research: 2 observational studies in people. The newest story, Oct 29, 2026: “Gut hormone drugs linked to serious hand and shoulder disorders”.

Disease

3 papers study it3 more mention it3 findings

1 new paper in 30 daysSee all 6

“The HR for a diagnosis of type 2 diabetes in participants with frozen shoulder versus people without frozen shoulder was 19.4 (95% confidence interval [CI] 15.6-24.0).”
Are patients with newly diagnosed frozen shoulder more likely to be diagnosed with type 2 diabetes? A cohort study in UK electronic health recordsDiabetes, obesity & metabolism2024doi:10.1111/dom.15965
  • Humans2
  • In silico1

Effects

1

Telomere length

downin silico1OR 0.9582

1 study

  1. Frozen shoulder decreases telomere length in silico (OR 0.9582, P = 0.0002).

    “FS influenced TL (OR 0.9582, P = 0.0002)”

    In silico

    Causal relationship between molecular markers of biological aging and orthopedic diseases: A two-sample bidirectional Mendelian randomization study

    Experimental gerontology

More on Telomere length

Associations

2

FGF23

upin silico1OR 1.2424

1 study

  1. FGF23 raises the risk of frozen shoulder in silico (OR 1.2424, P = 0.0316).

    “fibroblast growth factor-23 (FGF-23) impacted frozen shoulder (FS) (OR 1.2424, P = 0.0316)”

    In silico

    Causal relationship between molecular markers of biological aging and orthopedic diseases: A two-sample bidirectional Mendelian randomization study

    Experimental gerontology

More on FGF23

Type 2 diabetes

upin humans1HR 19.4

1 study

  1. Frozen shoulder is linked with a higher risk of type 2 diabetes in humans (HR 19.4 (95% CI 15.6-24.0)).

    “The HR for a diagnosis of type 2 diabetes in participants with frozen shoulder versus people without frozen shoulder was 19.4 (95% confidence interval [CI] 15.6-24.0).”

    Humans15.8 years

    Are patients with newly diagnosed frozen shoulder more likely to be diagnosed with type 2 diabetes? A cohort study in UK electronic health records

    Diabetes, obesity & metabolism

More on Type 2 diabetes

Trial sponsors

Latest

Nov 2025: 0Dec 2025: 1Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 12 papers in 12 months
medRxiv

Gut hormone drugs linked to serious hand and shoulder disorders

Across 210 placebo-controlled trials, the odds of serious disorders in one soft-tissue disease group were 3.88 times those with placebo.Across 210 placebo-controlled trials, the odds of serious disorders in one soft-tissue disease group were 3.88 times those with placebo.

Preprint: meta-analysis · 134,138 peopleInterventions
Paper

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