Familial Alzheimer's disease
5 papers
- Human trial1
- Humans1
- Animals1
- Model organisms1
Trial sponsors
Washington University School of Medicine
1 trialPhase 340 people
Latest
7 in 12 monthsJournal of Alzheimer's Disease Reports
The single cell origin of sporadic Alzheimer's disease: A developmental biallelic somatic mutation model
ReviewMechanisms
Behavioural Brain Research
Age-related emergence of behavioral deficits and amyloid pathology in the J20 mouse model of Alzheimer's disease
Experiments in miceMechanisms
Neurobiology of Disease
A C. elegans model of familial Alzheimer's disease shows age-dependent synaptic degeneration independent of amyloid β-peptide
Experiments in wormsSynapse
AAIC 2025 Abstract
Grey‐White matter contrast as an early brain pathology marker in Familial Alzheimer's disease
Cohort study of 70 peopleAlzheimer's disease
AAIC 2025 Abstract
Impact of genetic counseling and testing in individuals at high risk for Alzheimer ´s Disease from Latin America
Non-randomised trial in 122 peopleAlzheimer's disease
AAIC 2025 Abstract
Marmosets as Research Models of Alzheimer's Disease (MARMO‐AD)
Experiments in marmosetsMechanisms
Experimental Physiology
Role of S1P- and Rho-kinase signalling in age-related myogenic tone deficiency in murine resistance arteries
Experiments in miceMechanisms
Journal of Neural Transmission
Insights into insulin signalling and oxidative stress in the Tg2576 mouse model of familial Alzheimer's disease: effects of chronic oral galactose administration
Experiments in animalsInterventions
CNS Neuroscience & Therapeutics
Biological Effects of Dietary Restriction on Alzheimer's Disease: Experimental and Clinical Investigations
ReviewInterventions
Scientific Reports
Longitudinal characterization reveals behavioral impairments in aged APP knock in mouse models
Experiments in animalsMechanisms